If there is a paper you are interested in but cannot access it, please email Dr. Guthmiller and she will send it to you.
Peer-Reviewed Articles
*Contributed equally †Corresponding
Underlined and bolded names represent people in the Guthmiller lab
2023
Ji W, Guthmiller J†. Goldilocks Zone of Preexisting Immunity: Too Little or Too Much Suppresses Diverse Antibody Responses Against Influenza Viruses. Journal of Infectious Diseases. 2023 Nov 18:jiad494
Rappazzo CG, Fernández-Quintero ML, Mayer A, Wu NC, Greiff V, Guthmiller JJ†. Defining and Studying B cell Receptor and TCR Interactions. Journal of Immunology 2023 211 (3):311-322
Guthmiller JJ*†, Lan YL, Li L, Henry C, Stamper CT, Utset HA, Freyn AW, Han J, Stovicek O, Wang J, Zheng NY, Huang M, Dugan H, Tepora ME, Zhu X, Chen YQ, Palm AK, Shaw DG, Loganathan M, Francis BF, McNair M, Meade P, Wilson IA, García-Sastre A, Nachbagauer R, Palese P, Ward AB, Coughlan L, Krammer F, Wilson PC†. B cell convergence to distinct broadly reactive epitopes following vaccination with chimeric influenza virus hemagglutinins. Research Square. doi.org/10.21203/rs.3.rs-2600472/v1
2022
Good MR and Guthmiller JJ†. Female antibodies going the distance against influenza viruses. mBio 2022 Sep 12;e0210622.
Li L, Changrob S, Fu Y, Stovicek O, Guthmiller JJ, McGrath J, Dugan H, Stamper CT, Zheng NY, Huang M, Wilson PC. Librator: a platform for the optimized analysis, design, and expression of mutable influenza viral antigens. Briefings in Bioinformatics. 2022 Mar 10; 23(2):bbac028
Guthmiller JJ*†, Han J*, Utset HA, Li L, Lan YL, Henry C, Stamper CT, McMahon M, O’Dell G, Fernández-Quintero M, Freyn AW, Amanat F, Stovicek O, Gentles L, Richey ST, Torrents de la Peña A, Rosado V, Dugan H, Zheng NY, Tepora ME, Bitar DJ, Changrob S, Strohmeier S, Huang M, García-Sastre A, Liedl KR, Bloom JD, Nachbagauer R, Palese P, Krammer F, Coughlan L, Ward AB†, Wilson PC†. Broadly neutralizing antibodies target a hemagglutinin anchor epitope. Nature. 2022 Feb;602(7896):314-320
2021
Changrob S*, Fu Y*, Guthmiller JJ*, Halfmann PJ, Li L, Stamper CT, Dugan HL, Accola M, Rehrauer W, Zheng NY, Huang M, Wang J, Erickson SA, Utset HA, Graves HM, Amanat F, Sather DN, Krammer F, Kawaoka Y, Wilson PC†. Cross-neutralization of emerging SARS-CoV-2 variants of concern by antibodies targeting distinct epitopes on spike. mBio. 2021 Nov 16;:e0297521
Guthmiller JJ†, Utset HA, Henry C, Li L, Zheng NY, Sun W, Vieira MC, Zost S, Huang M, Hensley SE, Cobey S, Palese P, Wilson PC†. An egg-derived sulfated N-acetyllactosamine glycan is an antigenic decoy of influenza virus vaccines. mBio. 2021 Jun 15;:e0083821.
Guthmiller JJ*†, Han J*, Li L, Freyn AW, Liu STH, Stovicek O, Stamper ST, Dugan HL, Tepora ME, Bitar DJ, Hamel NJ, Changrob S, Zheng NY, Huang M, Utset H, Krammer, F, Nachbagauer R, Palese P, Ward AB†, Wilson PC†. First exposure to the pandemic H1N1 virus induced broadly neutralizing antibodies targeting hemagglutinin head epitopes. Science Translational Medicine. 2021, Jun 2; 13(596).
Utset, HA, Guthmiller JJ†, Wilson PC. Bridging the B cell gap: novel technologies to study antigen-specific human B cell responses. Vaccines. 2021, 2021
Guthmiller JJ†, Utset HA, Wilson PC. B cell responses against influenza viruses: short-lived humoral immunity against a life-long threat. Viruses. 2021, 13(6), 965.
Dugan H, Stamper CT, Li L, Changrob S, Asby N, Halfmann P, Zheng NY, Haung M, Shaw D, Cobb M, Erickson S, Guthmiller JJ, Stovicek O, Wang J, Winkler E, Madariaga ML, Shanmugarajah K, Jansen M, Amanat F, Stewart I, Utset HA, Huang J, Nelson C, Dai YN, Hall P, Jedrzejczak R, Joachimiak A, Krammer F, Diamond M, Fremont D, Kawaoka Y, Wilson PC†. COVID-19 infection induces substantial memory B cell maturation to non-neutralizing viral targets. Immunity. 2021 Jun 8;54(6):1290-1303.
Vijay R*, Guthmiller JJ*, Sturtz A, Crooks S, Johnson J, Li L, YL Lan, Pope R, Chen Y, Rogers K, Dutta N, Toombs J, Wilson M, Wilson PC, Maury W, Brekken R, Butler NS†. Hemolysis-associated phosphatidylserine exposure promote polyclonal plasmablast differentiation. Journal of Experimental Medicine. 2021 Jun 7; 218(6).
Freyn AW, Han J, Guthmiller JJ, Bailey MJ, Neu K, Turner HL, Rosado VC, Chromikova V, Huang M, Strohmeier S, Liu STH, Simon V, Krammer F, Ward AB, Palese P, Wilson PC, Nachbagauer R†. Influenza hemagglutinin-specific IgA Fc-effector functionality is restricted to the stalk epitopes. Proceedings of the National Academy of Sciences. 2021 118(8)e21018102118.
Surette F*, Guthmiller JJ*, Li L, Sturtz A, Vijay R, Pope R, McClennan B, Pack A, Zander R, Shao P, Lan YL, Fernandez-Ruiz D, Heath W, Wilson PC, Butler NS†. Extrafollicular CD4 T cell-derived IL-10 functions rapidly and transiently to support anti-Plasmodium humoral immunity. Plos Pathogens. 2021 Feb;17(2):e1009288.
Guthmiller JJ*†, Stovicek O*, Wang J*, Changrob S, Li L, Halfmann P, Zheng NY, Utset H, Stamper CT, Dugan H, Miller WD, Huang M, Jansen M, Shanmugarajah K, Donington J, Krammer F, Fremont D, Joachimiak A, Kawaoka Y, Tesic V, Madariaga ML, Wilson PC†. SARS-CoV-2 infection severity is linked to superior humoral immunity against the spike. mBio. 2021 Jan 19; 12:e02940-20. #Featured on Vincent Racaniello’s Immune podcast
Madariaga ML†, Guthmiller JJ, Schrantz S, Jansen M, Chancey C, Kumar, M, Prochaska M, Wool G, Durkin A, Oh WH, Trockman L, Vigneswaran J, Keskey R, Shaw DG, Dugan H, Zheng NY, Cobb M, Utset H, Wang J, Stovicek O, Bethel C, Matushek S, Giurcanu, Beavis K, Meltzer D, Ferguson M, Kress JP, Shanmugarajah K, Matthews J, Fung J, Wilson PC, Alverdy J, Donnington, J. Clinical predictors of donor antibody titer and correlation with recipient antibody response in a COVID-19 convalescent plasma clinical trial. Journal of Internal Medicine. 2021 Apr;289(4):559-573.
2020
Guthmiller JJ, Lan YL, Fernández-Quintero M, Han J, Bitar D, Hamel N, Stovicek O, Li L, Tepora M, Henry C, Neu K, Dugan H, Chen YQ, Liu STH, Stamper CT, Zheng NY, Huang M, Palm AKE, García-Sastre A, Nachbagauer R, Palese P, Coughlan L, Krammer F, Ward AB, Liedl K, Wilson PC†. Polyreactive broadly neutralizing B cells are selected to provide defense against pandemic threat influenza viruses. Immunity. 2020 Dec 15;53(6):1230-1244.
Guthmiller JJ, Wilson PC†. Remembering seasonal coronaviruses. Science. 2020 Dec. 11;370(6522):1272-1273.
Dugan HL*, Guthmiller JJ*, Arevalo P, Huang M, Chen Y-Q, Neu KE, Henry C, Zheng N-Y, Lan YL, Tepora ME, Stovicek O, Bitar D, Palm AK, Stamper CS, Changrob S, Utset HA, Coughlan L, Krammer F, Cobey, Wilson PC†. Pre-existing immunity shapes distinct antibody landscapes following influenza virus infection and vaccination. Science Translational Medicine. 2020 Dec 9;12(573)
Boughter CT, Borowska MT, Guthmiller JJ, Bendelac A, Wilson PC, Roux B, Adams EJ†. Biochemical patterns of antibody polyreactivity revealed through a bioinformatics-based analysis of CDR loops. eLife. 2020 Nov 10;9
Vijay R*, Guthmiller JJ*, Sturtz AJ, Surette FA, Li F, Sompallae RR, Rogers KJ, Pope RL, Chan J-A, de Labastida Rivera F, Andrew D, Webb L, Maury W, Que H-H, Engwerda CR, McCarthy JS, Boyle MJ, Butler NS†. Infection-induced plasmablasts are a nutrient sink that impairs humoral immunity to malaria. Nature Immunology. 2020 Jul;21(7):790-801.
Guthmiller JJ, Wilson PC. It’s hard to teach old B cells new tricks. Cell. 2020 Jan 9;180(1):18-20.
Bernstein DI, Guptill J, Naficy A, Nachbagauer R, Berlanda-Scorza F, Feser J, Wilson PC, Solórzano A, Van der Wielen M, Walter EB, Albrecht RA, Buschle KN, Chen YQ, Claeys C, Dickey M, Dugan HL, Ermler ME, Freeman D, Gao M, Gast C, Guthmiller JJ, Hai R, Henry C, Lan LY, McNeal M, Palm AE, Shaw DG, Stamper CT, Sun W, Sutton V, Tepora ME, Wahid R, Wenzel H, Wohlbold TJ, Innis BL, García-Sastre A, Palese P, Krammer F†. Immunogenicity of chimeric haemagglutinin-based, universal influenza virus vaccine candidates: interim results of a randomised, placebo-controlled, phase 1 clinical trial. Lancet Infectious Diseases. 2020 Jan:20(1):80-91.
2019
Hagan T, Cortese M, Rouphael N, Boudreau C, Linde C, Maddur MS, Das J, Wang H, Guthmiller J, Zheng NY, Huang M, Uphadhyay AA, Gardinassi L, Petitdemange C, McCullough MP, Johnson SJ, Gill K, Cervasi B, Zou J, Bretin A, Hahn M, Gewirtz AT, Bosinger SE, Wilson PC, Li S, Alter G, Khurana S, Golding H, Pulendran B†. Antibiotics-Driven Gut Microbiome Perturbation Alters Immunity to Vaccines in Humans. Cell. 2019 Sep 5:178(6):1313-1328.e13.
Guthmiller JJ, Dugan HL, Neu KE, Lan, YL, Wilson PC†. An efficient method to generate monoclonal antibodies from a single human B cell. Methods in Molecular Biology. 2019;1904:109-145.
Neu KE*, Guthmiller JJ*, Zheng NY, Huang M, La J, Veira MC, Kim K, Cortese M, Tepora ME, Hamel NJ, Rojas KT, Henry CJ, Shaw D, Dulberger CL, Pulendran B, Cobey S, Khan AA, Wilson PC†. Spec-seq unveils transcriptional subpopulations of antibody-secreting cells following influenza vaccination. Journal of Clinical Investigation. 2019 Jan 2;129(1):93-105
2018
Guthmiller JJ and Wilson PC†. Harnessing immune history to combat influenza viruses. Current Opinion in Immunology. 2018 Aug;53:187-195.
Smith LK, Boukhaled GM, Condotta SA, Mazouz S, Guthmiller JJ, Vijay R, Butler NS, Bruneau J, Shoukry NH, Krawczyk CM, Richer MJ†. IL-10 directly inhibits CD8 T cell function by altering N-glycan branching. Immunity. 2018 Feb 20;48(2):299-312.
2017
Zander RA, Vijay R, Pack AD, Guthmiller JJ, Graham AC, Lindner SE, Vaughan AM, Kappe S, and Butler NS†. Th1-like Plasmodium-specific memory CD4+ T cells support humoral immunity. Cell Reports. 2017 Nov 14;21(7):1839-1852.
Rivera-Correa J, Guthmiller JJ, Vijay R, Fernandez-Arias C, Pardo-Ruge MA, Gonzalez S, Butler NS, and Rodriguez A†. Plasmodium direct activation of T-bet+ B cells leads to autoimmune anemia during malaria. Nature Communications. 2017 Nov 3;8(1):1282.
Guthmiller JJ, Graham AC, Zander RA, Pope RL, Butler NS†. Cutting edge: IL-10 is essential for the generation of germinal center B cells and anti-Plasmodium humoral immunity. Journal of Immunology. 2017 Jan 15;198(2):617-622.
2016
Zander RA, Guthmiller JJ, Graham AC, Pope RL, Burke BE, Carr DJ, Butler NS†. Type I interferons induce T regulatory 1 responses and restrict humoral immunity during experimental malaria. Plos Pathogens. 2016 Oct;12(10):e1005945.
2015
Zander RA, Obeng-Adjei N, Guthmiller JJ, Kulu DI, Li J, Ongoiba A, Traore B, Crompton PD and Butler NS†. PD-1 co-inhibitory and OX40 co-stimulatory crosstalk regulates helper T cell differentiation and anti-Plasmodium humoral immunity. Cell Host & Microbe. 2015 May 13;17(5):628-41.
Guthmiller JJ*, Zander RA*, Butler NS†. Measurement of the T cell response to pre-erythrocytic vaccination in mice. Methods in Molecular Biology. 2015;1325:19-37.
Peer-Reviewed Articles
*Contributed equally †Corresponding
Underlined and bolded names represent people in the Guthmiller lab
2023
Ji W, Guthmiller J†. Goldilocks Zone of Preexisting Immunity: Too Little or Too Much Suppresses Diverse Antibody Responses Against Influenza Viruses. Journal of Infectious Diseases. 2023 Nov 18:jiad494
Rappazzo CG, Fernández-Quintero ML, Mayer A, Wu NC, Greiff V, Guthmiller JJ†. Defining and Studying B cell Receptor and TCR Interactions. Journal of Immunology 2023 211 (3):311-322
Guthmiller JJ*†, Lan YL, Li L, Henry C, Stamper CT, Utset HA, Freyn AW, Han J, Stovicek O, Wang J, Zheng NY, Huang M, Dugan H, Tepora ME, Zhu X, Chen YQ, Palm AK, Shaw DG, Loganathan M, Francis BF, McNair M, Meade P, Wilson IA, García-Sastre A, Nachbagauer R, Palese P, Ward AB, Coughlan L, Krammer F, Wilson PC†. B cell convergence to distinct broadly reactive epitopes following vaccination with chimeric influenza virus hemagglutinins. Research Square. doi.org/10.21203/rs.3.rs-2600472/v1
2022
Good MR and Guthmiller JJ†. Female antibodies going the distance against influenza viruses. mBio 2022 Sep 12;e0210622.
Li L, Changrob S, Fu Y, Stovicek O, Guthmiller JJ, McGrath J, Dugan H, Stamper CT, Zheng NY, Huang M, Wilson PC. Librator: a platform for the optimized analysis, design, and expression of mutable influenza viral antigens. Briefings in Bioinformatics. 2022 Mar 10; 23(2):bbac028
Guthmiller JJ*†, Han J*, Utset HA, Li L, Lan YL, Henry C, Stamper CT, McMahon M, O’Dell G, Fernández-Quintero M, Freyn AW, Amanat F, Stovicek O, Gentles L, Richey ST, Torrents de la Peña A, Rosado V, Dugan H, Zheng NY, Tepora ME, Bitar DJ, Changrob S, Strohmeier S, Huang M, García-Sastre A, Liedl KR, Bloom JD, Nachbagauer R, Palese P, Krammer F, Coughlan L, Ward AB†, Wilson PC†. Broadly neutralizing antibodies target a hemagglutinin anchor epitope. Nature. 2022 Feb;602(7896):314-320
2021
Changrob S*, Fu Y*, Guthmiller JJ*, Halfmann PJ, Li L, Stamper CT, Dugan HL, Accola M, Rehrauer W, Zheng NY, Huang M, Wang J, Erickson SA, Utset HA, Graves HM, Amanat F, Sather DN, Krammer F, Kawaoka Y, Wilson PC†. Cross-neutralization of emerging SARS-CoV-2 variants of concern by antibodies targeting distinct epitopes on spike. mBio. 2021 Nov 16;:e0297521
Guthmiller JJ†, Utset HA, Henry C, Li L, Zheng NY, Sun W, Vieira MC, Zost S, Huang M, Hensley SE, Cobey S, Palese P, Wilson PC†. An egg-derived sulfated N-acetyllactosamine glycan is an antigenic decoy of influenza virus vaccines. mBio. 2021 Jun 15;:e0083821.
Guthmiller JJ*†, Han J*, Li L, Freyn AW, Liu STH, Stovicek O, Stamper ST, Dugan HL, Tepora ME, Bitar DJ, Hamel NJ, Changrob S, Zheng NY, Huang M, Utset H, Krammer, F, Nachbagauer R, Palese P, Ward AB†, Wilson PC†. First exposure to the pandemic H1N1 virus induced broadly neutralizing antibodies targeting hemagglutinin head epitopes. Science Translational Medicine. 2021, Jun 2; 13(596).
Utset, HA, Guthmiller JJ†, Wilson PC. Bridging the B cell gap: novel technologies to study antigen-specific human B cell responses. Vaccines. 2021, 2021
Guthmiller JJ†, Utset HA, Wilson PC. B cell responses against influenza viruses: short-lived humoral immunity against a life-long threat. Viruses. 2021, 13(6), 965.
Dugan H, Stamper CT, Li L, Changrob S, Asby N, Halfmann P, Zheng NY, Haung M, Shaw D, Cobb M, Erickson S, Guthmiller JJ, Stovicek O, Wang J, Winkler E, Madariaga ML, Shanmugarajah K, Jansen M, Amanat F, Stewart I, Utset HA, Huang J, Nelson C, Dai YN, Hall P, Jedrzejczak R, Joachimiak A, Krammer F, Diamond M, Fremont D, Kawaoka Y, Wilson PC†. COVID-19 infection induces substantial memory B cell maturation to non-neutralizing viral targets. Immunity. 2021 Jun 8;54(6):1290-1303.
Vijay R*, Guthmiller JJ*, Sturtz A, Crooks S, Johnson J, Li L, YL Lan, Pope R, Chen Y, Rogers K, Dutta N, Toombs J, Wilson M, Wilson PC, Maury W, Brekken R, Butler NS†. Hemolysis-associated phosphatidylserine exposure promote polyclonal plasmablast differentiation. Journal of Experimental Medicine. 2021 Jun 7; 218(6).
Freyn AW, Han J, Guthmiller JJ, Bailey MJ, Neu K, Turner HL, Rosado VC, Chromikova V, Huang M, Strohmeier S, Liu STH, Simon V, Krammer F, Ward AB, Palese P, Wilson PC, Nachbagauer R†. Influenza hemagglutinin-specific IgA Fc-effector functionality is restricted to the stalk epitopes. Proceedings of the National Academy of Sciences. 2021 118(8)e21018102118.
Surette F*, Guthmiller JJ*, Li L, Sturtz A, Vijay R, Pope R, McClennan B, Pack A, Zander R, Shao P, Lan YL, Fernandez-Ruiz D, Heath W, Wilson PC, Butler NS†. Extrafollicular CD4 T cell-derived IL-10 functions rapidly and transiently to support anti-Plasmodium humoral immunity. Plos Pathogens. 2021 Feb;17(2):e1009288.
Guthmiller JJ*†, Stovicek O*, Wang J*, Changrob S, Li L, Halfmann P, Zheng NY, Utset H, Stamper CT, Dugan H, Miller WD, Huang M, Jansen M, Shanmugarajah K, Donington J, Krammer F, Fremont D, Joachimiak A, Kawaoka Y, Tesic V, Madariaga ML, Wilson PC†. SARS-CoV-2 infection severity is linked to superior humoral immunity against the spike. mBio. 2021 Jan 19; 12:e02940-20. #Featured on Vincent Racaniello’s Immune podcast
Madariaga ML†, Guthmiller JJ, Schrantz S, Jansen M, Chancey C, Kumar, M, Prochaska M, Wool G, Durkin A, Oh WH, Trockman L, Vigneswaran J, Keskey R, Shaw DG, Dugan H, Zheng NY, Cobb M, Utset H, Wang J, Stovicek O, Bethel C, Matushek S, Giurcanu, Beavis K, Meltzer D, Ferguson M, Kress JP, Shanmugarajah K, Matthews J, Fung J, Wilson PC, Alverdy J, Donnington, J. Clinical predictors of donor antibody titer and correlation with recipient antibody response in a COVID-19 convalescent plasma clinical trial. Journal of Internal Medicine. 2021 Apr;289(4):559-573.
2020
Guthmiller JJ, Lan YL, Fernández-Quintero M, Han J, Bitar D, Hamel N, Stovicek O, Li L, Tepora M, Henry C, Neu K, Dugan H, Chen YQ, Liu STH, Stamper CT, Zheng NY, Huang M, Palm AKE, García-Sastre A, Nachbagauer R, Palese P, Coughlan L, Krammer F, Ward AB, Liedl K, Wilson PC†. Polyreactive broadly neutralizing B cells are selected to provide defense against pandemic threat influenza viruses. Immunity. 2020 Dec 15;53(6):1230-1244.
Guthmiller JJ, Wilson PC†. Remembering seasonal coronaviruses. Science. 2020 Dec. 11;370(6522):1272-1273.
Dugan HL*, Guthmiller JJ*, Arevalo P, Huang M, Chen Y-Q, Neu KE, Henry C, Zheng N-Y, Lan YL, Tepora ME, Stovicek O, Bitar D, Palm AK, Stamper CS, Changrob S, Utset HA, Coughlan L, Krammer F, Cobey, Wilson PC†. Pre-existing immunity shapes distinct antibody landscapes following influenza virus infection and vaccination. Science Translational Medicine. 2020 Dec 9;12(573)
Boughter CT, Borowska MT, Guthmiller JJ, Bendelac A, Wilson PC, Roux B, Adams EJ†. Biochemical patterns of antibody polyreactivity revealed through a bioinformatics-based analysis of CDR loops. eLife. 2020 Nov 10;9
Vijay R*, Guthmiller JJ*, Sturtz AJ, Surette FA, Li F, Sompallae RR, Rogers KJ, Pope RL, Chan J-A, de Labastida Rivera F, Andrew D, Webb L, Maury W, Que H-H, Engwerda CR, McCarthy JS, Boyle MJ, Butler NS†. Infection-induced plasmablasts are a nutrient sink that impairs humoral immunity to malaria. Nature Immunology. 2020 Jul;21(7):790-801.
Guthmiller JJ, Wilson PC. It’s hard to teach old B cells new tricks. Cell. 2020 Jan 9;180(1):18-20.
Bernstein DI, Guptill J, Naficy A, Nachbagauer R, Berlanda-Scorza F, Feser J, Wilson PC, Solórzano A, Van der Wielen M, Walter EB, Albrecht RA, Buschle KN, Chen YQ, Claeys C, Dickey M, Dugan HL, Ermler ME, Freeman D, Gao M, Gast C, Guthmiller JJ, Hai R, Henry C, Lan LY, McNeal M, Palm AE, Shaw DG, Stamper CT, Sun W, Sutton V, Tepora ME, Wahid R, Wenzel H, Wohlbold TJ, Innis BL, García-Sastre A, Palese P, Krammer F†. Immunogenicity of chimeric haemagglutinin-based, universal influenza virus vaccine candidates: interim results of a randomised, placebo-controlled, phase 1 clinical trial. Lancet Infectious Diseases. 2020 Jan:20(1):80-91.
2019
Hagan T, Cortese M, Rouphael N, Boudreau C, Linde C, Maddur MS, Das J, Wang H, Guthmiller J, Zheng NY, Huang M, Uphadhyay AA, Gardinassi L, Petitdemange C, McCullough MP, Johnson SJ, Gill K, Cervasi B, Zou J, Bretin A, Hahn M, Gewirtz AT, Bosinger SE, Wilson PC, Li S, Alter G, Khurana S, Golding H, Pulendran B†. Antibiotics-Driven Gut Microbiome Perturbation Alters Immunity to Vaccines in Humans. Cell. 2019 Sep 5:178(6):1313-1328.e13.
Guthmiller JJ, Dugan HL, Neu KE, Lan, YL, Wilson PC†. An efficient method to generate monoclonal antibodies from a single human B cell. Methods in Molecular Biology. 2019;1904:109-145.
Neu KE*, Guthmiller JJ*, Zheng NY, Huang M, La J, Veira MC, Kim K, Cortese M, Tepora ME, Hamel NJ, Rojas KT, Henry CJ, Shaw D, Dulberger CL, Pulendran B, Cobey S, Khan AA, Wilson PC†. Spec-seq unveils transcriptional subpopulations of antibody-secreting cells following influenza vaccination. Journal of Clinical Investigation. 2019 Jan 2;129(1):93-105
2018
Guthmiller JJ and Wilson PC†. Harnessing immune history to combat influenza viruses. Current Opinion in Immunology. 2018 Aug;53:187-195.
Smith LK, Boukhaled GM, Condotta SA, Mazouz S, Guthmiller JJ, Vijay R, Butler NS, Bruneau J, Shoukry NH, Krawczyk CM, Richer MJ†. IL-10 directly inhibits CD8 T cell function by altering N-glycan branching. Immunity. 2018 Feb 20;48(2):299-312.
2017
Zander RA, Vijay R, Pack AD, Guthmiller JJ, Graham AC, Lindner SE, Vaughan AM, Kappe S, and Butler NS†. Th1-like Plasmodium-specific memory CD4+ T cells support humoral immunity. Cell Reports. 2017 Nov 14;21(7):1839-1852.
Rivera-Correa J, Guthmiller JJ, Vijay R, Fernandez-Arias C, Pardo-Ruge MA, Gonzalez S, Butler NS, and Rodriguez A†. Plasmodium direct activation of T-bet+ B cells leads to autoimmune anemia during malaria. Nature Communications. 2017 Nov 3;8(1):1282.
Guthmiller JJ, Graham AC, Zander RA, Pope RL, Butler NS†. Cutting edge: IL-10 is essential for the generation of germinal center B cells and anti-Plasmodium humoral immunity. Journal of Immunology. 2017 Jan 15;198(2):617-622.
2016
Zander RA, Guthmiller JJ, Graham AC, Pope RL, Burke BE, Carr DJ, Butler NS†. Type I interferons induce T regulatory 1 responses and restrict humoral immunity during experimental malaria. Plos Pathogens. 2016 Oct;12(10):e1005945.
2015
Zander RA, Obeng-Adjei N, Guthmiller JJ, Kulu DI, Li J, Ongoiba A, Traore B, Crompton PD and Butler NS†. PD-1 co-inhibitory and OX40 co-stimulatory crosstalk regulates helper T cell differentiation and anti-Plasmodium humoral immunity. Cell Host & Microbe. 2015 May 13;17(5):628-41.
Guthmiller JJ*, Zander RA*, Butler NS†. Measurement of the T cell response to pre-erythrocytic vaccination in mice. Methods in Molecular Biology. 2015;1325:19-37.